Image:CTLA4 Crystal Structure.rsh.png
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This is an image of murine CTLA4 (CD152) which is necessary for inhibiting the T cells. It binds to CD28 with a higher affinity than the costimulatory molecules CD80 and CD86. This image is derived from Protein Data Bank data 1DQT which was published by Ostrov et al in 2000. I rendered the image in PyMol myself based on the published pdb file.
For the published pdb, please see: Ostrov, D.A., Shi, W., Schwartz, J.C., Almo, S.C., Nathenson, S.G. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science v290 pp.816-819 , 2000.
| Description |
Crystal structure of CTLA4 as published in the Protein Data Bank (PDB: 1DQT) |
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| Source |
Created from PDB 1DQT and rendered by me using Pymol |
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| Date |
12-10-2006 |
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| Author |
Ramin Herati |
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| Permission (Reusing this image) |
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File history
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| Date/Time | Dimensions | User | Comment | |
|---|---|---|---|---|
| current | 02:37, 11 December 2006 | 739×750 (244 KB) | Sedmic | (This is an image of murine CTLA4 (CD152) which is necessary for inhibiting the T cells. It binds to CD28 with a higher affinity than the costimulatory molecules CD80 and CD86. This image is derived from Protein Data Bank data 1DQT which was published by O) |
