CSTF2T

From Wikipedia, the free encyclopedia

Cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant

PDB rendering based on 1p1t.

Available structures: 1p1t, 2j8p

Identifiers

Symbol(s)

CSTF2T; CstF-64T; DKFZp434C1013; KIAA0689

External IDs

MGI: 1932622 HomoloGene: 80230

Gene ontology
Molecular Function:	• nucleotide binding • RNA binding
Cellular Component:	• intracellular • nucleus
Biological Process:	• mRNA processing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_015235 (mRNA)
NP_056050 (protein)

NM_031249 (mRNA)
NP_112539 (protein)

Location

Chr 10: 53.13 - 53.13 Mb

Chr 19: 31.15 - 31.15 Mb

Pubmed search

[1]

[2]

Cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant, also known as CSTF2T, is a human gene.^[1]

[edit] References

^ Entrez Gene: CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Ishikawa K, Nagase T, Suyama M, et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.". DNA Res. 5 (3): 169–76. PMID 9734811.
Dass B, McMahon KW, Jenkins NA, et al. (2001). "The gene for a variant form of the polyadenylation protein CstF-64 is on chromosome 19 and is expressed in pachytene spermatocytes in mice.". J. Biol. Chem. 276 (11): 8044–50. doi:10.1074/jbc.M009091200. PMID 11113135.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Dass B, McDaniel L, Schultz RA, et al. (2003). "The gene CSTF2T, encoding the human variant CstF-64 polyadenylation protein tauCstF-64, lacks introns and may be associated with male sterility.". Genomics 80 (5): 509–14. PMID 12408968.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Pérez Cañadillas JM, Varani G (2003). "Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein.". EMBO J. 22 (11): 2821–30. doi:10.1093/emboj/cdg259. PMID 12773396.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Zhao X, Oberg D, Rush M, et al. (2005). "A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein.". J. Virol. 79 (7): 4270–88. doi:10.1128/JVI.79.7.4270-4288.2005. PMID 15767428.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.