CROCC

From Wikipedia, the free encyclopedia

Ciliary rootlet coiled-coil, rootletin

Identifiers

CROCC; KIAA0445

External IDs

Gene ontology
Molecular Function:	• structural molecule activity • kinesin binding
Cellular Component:	• centriole • ciliary rootlet
Biological Process:	• cell cycle • centrosome organization and biogenesis

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_014675 (mRNA)
NP_055490 (protein)

NM_172122 (mRNA)
NP_742120 (protein)

Location

n/a

Chr 4: 140.29 - 140.33 Mb

Pubmed search

[1]

[2]

Ciliary rootlet coiled-coil, rootletin, also known as CROCC, is a human gene.^[1]

[edit] References

^ Entrez Gene: CROCC ciliary rootlet coiled-coil, rootletin.

[edit] Further reading

Ching YP, Chan SF, Jeang KT, Jin DY (2006). "The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication.". Nat. Cell Biol. 8 (7): 717-24. doi:10.1038/ncb1432. PMID 16767081.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.
Bahe S, Stierhof YD, Wilkinson CJ, et al. (2005). "Rootletin forms centriole-associated filaments and functions in centrosome cohesion.". J. Cell Biol. 171 (1): 27-33. doi:10.1083/jcb.200504107. PMID 16203858.
Andersen JS, Wilkinson CJ, Mayor T, et al. (2003). "Proteomic characterization of the human centrosome by protein correlation profiling.". Nature 426 (6966): 570-4. doi:10.1038/nature02166. PMID 14654843.
Behrends U, Schneider I, Rössler S, et al. (2003). "Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries.". Int. J. Cancer 106 (2): 244-51. doi:10.1002/ijc.11208. PMID 12800201.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Yang J, Liu X, Yue G, et al. (2002). "Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet.". J. Cell Biol. 159 (3): 431-40. doi:10.1083/jcb.200207153. PMID 12427867.
Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.". DNA Res. 4 (5): 345-9. PMID 9455484.