CRIP1

From Wikipedia, the free encyclopedia

Cysteine-rich protein 1 (intestinal)

PDB rendering based on 1iml.

Available structures: 1iml

Identifiers

Symbol(s)

CRIP1; CRP1; CRHP; CRIP

External IDs

OMIM: 123875 MGI: 88501 HomoloGene: 37465

Gene ontology
Molecular Function:	• zinc ion binding • metal ion binding
Cellular Component:	• cytoplasm
Biological Process:	• cell proliferation • antimicrobial humoral response

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001311 (mRNA)
NP_001302 (protein)

NM_007763 (mRNA)
NP_031789 (protein)

Location

Chr 14: 105.02 - 105.03 Mb

Chr 12: 113.6 - 113.6 Mb

Pubmed search

[1]

[2]

Cysteine-rich protein 1 (intestinal), also known as CRIP1, is a human gene.^[1]

Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991).[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: CRIP1 cysteine-rich protein 1 (intestinal).

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Garcia-Barcelo M, Tsui SK, Chim SS, et al. (1998). "Mapping of the human cysteine-rich intestinal protein gene CRIP1 to the human chromosomal segment 7q11.23.". Genomics 47 (3): 419-22. doi:10.1006/geno.1997.5134. PMID 9480758.
Khoo C, Blanchard RK, Sullivan VK, Cousins RJ (1997). "Human cysteine-rich intestinal protein: cDNA cloning and expression of recombinant protein and identification in human peripheral blood mononuclear cells.". Protein Expr. Purif. 9 (3): 379-87. doi:10.1006/prep.1996.0709. PMID 9126610.
Khoo C, Cousins RJ (1994). "Purification and properties of rat cysteine-rich intestinal protein.". Biochem. J. 299 ( Pt 2): 445-50. PMID 8172605.
Tsui SK, Yam NY, Lee CY, Waye MM (1995). "Isolation and characterization of a cDNA that codes for a LIM-containing protein which is developmentally regulated in heart.". Biochem. Biophys. Res. Commun. 205 (1): 497-505. doi:10.1006/bbrc.1994.2693. PMID 7999070.
Hempe JM, Cousins RJ (1991). "Cysteine-rich intestinal protein binds zinc during transmucosal zinc transport.". Proc. Natl. Acad. Sci. U.S.A. 88 (21): 9671-4. PMID 1946385.