CPSF2

From Wikipedia, the free encyclopedia


Cleavage and polyadenylation specific factor 2, 100kDa
Identifiers
Symbol(s) CPSF2; CPSF100; KIAA1367
External IDs OMIM: 606028 MGI: 1861601 HomoloGene: 6460
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 53981 51786
Ensembl ENSG00000165934 ENSMUSG00000041781
Uniprot Q9P2I0 Q3UGU6
Refseq NM_017437 (mRNA)
NP_059133 (protein)		 NM_016856 (mRNA)
NP_058552 (protein)
Location Chr 14: 91.66 - 91.7 Mb Chr 12: 102.38 - 102.41 Mb
Pubmed search [1] [2]

Cleavage and polyadenylation specific factor 2, 100kDa, also known as CPSF2, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: CPSF2 cleavage and polyadenylation specific factor 2, 100kDa.

[edit] Further reading

  • Murthy KG, Manley JL (1995). "The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation.". Genes Dev. 9 (21): 2672–83. PMID 7590244. 
  • Jenny A, Hauri HP, Keller W (1994). "Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit.". Mol. Cell. Biol. 14 (12): 8183–90. PMID 7969155. 
  • Thuresson AC, Aström J, Aström A, et al. (1994). "Multiple forms of poly(A) polymerases in human cells.". Proc. Natl. Acad. Sci. U.S.A. 91 (3): 979–83. PMID 8302877. 
  • Bienroth S, Keller W, Wahle E (1993). "Assembly of a processive messenger RNA polyadenylation complex.". EMBO J. 12 (2): 585–94. PMID 8440247. 
  • Schul W, Groenhout B, Koberna K, et al. (1996). "The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA.". EMBO J. 15 (11): 2883–92. PMID 8654386. 
  • McCracken S, Fong N, Yankulov K, et al. (1997). "The C-terminal domain of RNA polymerase II couples mRNA processing to transcription.". Nature 385 (6614): 357–61. doi:10.1038/385357a0. PMID 9002523. 
  • Takagaki Y, Manley JL (2000). "Complex protein interactions within the human polyadenylation machinery identify a novel component.". Mol. Cell. Biol. 20 (5): 1515–25. PMID 10669729. 
  • Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (1): 65–73. PMID 10718198. 
  • Monsalve M, Wu Z, Adelmant G, et al. (2000). "Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1.". Mol. Cell 6 (2): 307–16. PMID 10983978. 
  • de Vries H, Rüegsegger U, Hübner W, et al. (2000). "Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors.". EMBO J. 19 (21): 5895–904. doi:10.1093/emboj/19.21.5895. PMID 11060040. 
  • Samiotaki M, Balatsos NA, Courtis N, Tsiapalis CM (2001). "Assignment of the 100-kDa subunit of cleavage and polyadenylation specificity factor (CPSF2) to human chromosome 14q31.3 by radiation hybrid mapping.". Cytogenet. Cell Genet. 90 (3-4): 328–9. PMID 11124543. 
  • Hodgman R, Tay J, Mendez R, Richter JD (2001). "CPEB phosphorylation and cytoplasmic polyadenylation are catalyzed by the kinase IAK1/Eg2 in maturing mouse oocytes.". Development 128 (14): 2815–22. PMID 11526086. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Kaufmann I, Martin G, Friedlein A, et al. (2005). "Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.". EMBO J. 23 (3): 616–26. doi:10.1038/sj.emboj.7600070. PMID 14749727. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
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