Coumestan
From Wikipedia, the free encyclopedia
| Coumestan | |
|---|---|
 |
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| IUPAC name | [1]Benzoxolo[3,2-c]chromen-6-one |
| Identifiers | |
| CAS number | [479-12-9] |
| PubChem | |
| SMILES | C1=CC=C2C(=C1)C3=C(O2)C4=CC=CC=C4OC3=O |
| Properties | |
| Molecular formula | C15H8O3 |
| Molar mass | 236.22 g mol-1 |
| Melting point |
187-188 °C[1] |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Coumestan is an organic compound that is a derivative of coumarin. Coumestan forms the central core of a variety of natural compounds known collectively as coumestans. Coumestans, including coumestrol, a phytoestrogen, are found in a variety of plants.
Because of the estegenic activity of some coumestans, a variety of syntheses have been developed that allow the preparation of coumestans so that their pharmacological effects can be explored.[2][3]
[edit] Coumestans
 Plicadin |
[edit] References
- ^ Singh, Rishi Pal; Singh, Daljeet (1985). "An elegant synthesis of 6H-benzofuro[3,2-c][1]benzopyran-6-ones". Heterocycles 23 (4): 903.
- ^ Yao, Tuanli; Yue, Dawei; Larock, Richard C (2005). "An Efficient Synthesis of Coumestrol and Coumestans by Iodocyclization and Pd-Catalyzed Intramolecular Lactonization". Journal of Organic Chemistry 70 (24): 9985–9989. doi:.
- ^ Takeda, Norihiko; Miyata, Okiko; Naito, Takeaki (2007). "Efficient synthesis of benzofurans utilizing [3,3]-sigmatropic rearrangement triggered by N-trifluoroacetylation of oxime ethers: short synthesis of natural 2-arylbenzofurans". European Journal of Organic Chemistry 2007 (9): 1491–1509. doi:.
