COPB1

From Wikipedia, the free encyclopedia

Coatomer protein complex, subunit beta 1

Identifiers

COPB1; COPB; DKFZp761K102; FLJ10341

External IDs

OMIM: 600959 MGI: 1917599 HomoloGene: 5664

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• Golgi membrane • Golgi apparatus • Golgi-associated vesicle • cytosol • membrane • COPI vesicle coat
Biological Process:	• protein targeting • retrograde vesicle-mediated transport, Golgi to ER • intra-Golgi vesicle-mediated transport • protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_016451 (mRNA)
NP_057535 (protein)

NM_033370 (mRNA)
NP_203534 (protein)

Location

Chr 11: 14.44 - 14.48 Mb

Chr 7: 114.01 - 114.05 Mb

Pubmed search

[1]

[2]

Coatomer protein complex, subunit beta 1, also known as COPB1, is a human gene.

[edit] Further reading

Benichou S, Liu LX, Erdtmann L, et al. (1997). "Use of the two-hybrid system to identify cellular partners of the HIV1 Nef protein.". Res. Virol. 148 (1): 71–3. PMID 9017839.
Geyer M, Fackler OT, Peterlin BM (2001). "Structure--function relationships in HIV-1 Nef.". EMBO Rep. 2 (7): 580–5. doi:10.1093/embo-reports/kve141. PMID 11463741.
Duden R, Griffiths G, Frank R, et al. (1991). "Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin.". Cell 64 (3): 649–65. PMID 1840503.
Waters MG, Serafini T, Rothman JE (1991). "'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles.". Nature 349 (6306): 248–51. doi:10.1038/349248a0. PMID 1898986.
Benichou S, Bomsel M, Bodéus M, et al. (1994). "Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.". J. Biol. Chem. 269 (48): 30073–6. PMID 7982906.
Orcl L, Palmer DJ, Amherdt M, Rothman JE (1993). "Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol.". Nature 364 (6439): 732–4. doi:10.1038/364732a0. PMID 8355790.
Aniento F, Gu F, Parton RG, Gruenberg J (1996). "An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes.". J. Cell Biol. 133 (1): 29–41. PMID 8601610.
Lowe M, Kreis TE (1997). "In vivo assembly of coatomer, the COP-I coat precursor.". J. Biol. Chem. 271 (48): 30725–30. PMID 8940050.
Hansen K, Rönnstrand L, Rorsman C, et al. (1997). "Association of coatomer proteins with the beta-receptor for platelet-derived growth factor.". Biochem. Biophys. Res. Commun. 235 (3): 455–60. doi:10.1006/bbrc.1997.6821. PMID 9207175.
Pavel J, Harter C, Wieland FT (1998). "Reversible dissociation of coatomer: functional characterization of a beta/delta-coat protein subcomplex.". Proc. Natl. Acad. Sci. U.S.A. 95 (5): 2140–5. PMID 9482852.
Piguet V, Gu F, Foti M, et al. (1999). "Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes.". Cell 97 (1): 63–73. PMID 10199403.
Zhao L, Helms JB, Brunner J, Wieland FT (1999). "GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23.". J. Biol. Chem. 274 (20): 14198–203. PMID 10318838.
Fischer KD, Helms JB, Zhao L, Wieland FT (2000). "Site-specific photocrosslinking to probe interactions of Arf1 with proteins involved in budding of COPI vesicles.". Methods 20 (4): 455–64. doi:10.1006/meth.2000.0958. PMID 10720466.
Allan BB, Moyer BD, Balch WE (2000). "Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion.". Science 289 (5478): 444–8. PMID 10903204.
Eugster A, Frigerio G, Dale M, Duden R (2000). "COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP.". EMBO J. 19 (15): 3905–17. doi:10.1093/emboj/19.15.3905. PMID 10921873.
Sullivan BM, Harrison-Lavoie KJ, Marshansky V, et al. (2000). "RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport.". Mol. Biol. Cell 11 (9): 3155–68. PMID 10982407.
Futatsumori M, Kasai K, Takatsu H, et al. (2001). "Identification and characterization of novel isoforms of COP I subunits.". J. Biochem. 128 (5): 793–801. PMID 11056392.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.