Connexin-32 internal ribosome entry site (IRES)

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Connexin-32 internal ribosome entry site (IRES)
Template:Abbreviation
Type: Cis-reg; IRES;
2° structure: Published; PubMed
Seed alignment: Moxon SJ
Avg length: 147.5 nucleotides
Avg identity: 93%

The connexin-32 internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of connexin-32 and allows cap-independent translation. This internal ribosome entry site (IRES) allows cap independent translation during conditions such as heat shock and stress.[1]

[edit] References

  1. ^ Hudder, A; Werner R (2000). "Analysis of a Charcot-Marie-Tooth disease mutation reveals an essential internal ribosome entry site element in the connexin-32 gene". J Biol Chem 275: 34586–34591. doi:10.1074/jbc.M005199200. PMID 10931843. 

[edit] External links