COMMD1

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Copper metabolism (Murr1) domain containing 1
PDB rendering based on 2h2m.
Available structures: 2h2m
Identifiers
Symbol(s) COMMD1; C2orf5; MGC27155; MURR1
External IDs OMIM: 607238 MGI: 109474 HomoloGene: 17604
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 150684 17846
Ensembl ENSG00000173163 ENSMUSG00000051355
Uniprot Q8N668 Q3UGT3
Refseq NM_152516 (mRNA)
NP_689729 (protein)		 NM_144514 (mRNA)
NP_653097 (protein)
Location Chr 2: 61.99 - 62.22 Mb Chr 11: 22.8 - 22.88 Mb
Pubmed search [1] [2]

Copper metabolism (Murr1) domain containing 1, also known as COMMD1, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: COMMD1 copper metabolism (Murr1) domain containing 1.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
  • Nabetani A, Hatada I, Morisaki H, et al. (1997). "Mouse U2af1-rs1 is a neomorphic imprinted gene.". Mol. Cell. Biol. 17 (2): 789-98. PMID 9001233. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol. 19 (5): 440-5. doi:10.1038/88107. PMID 11329013. 
  • van De Sluis B, Rothuizen J, Pearson PL, et al. (2002). "Identification of a new copper metabolism gene by positional cloning in a purebred dog population.". Hum. Mol. Genet. 11 (2): 165-73. PMID 11809725. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Müller T, van de Sluis B, Zhernakova A, et al. (2003). "The canine copper toxicosis gene MURR1 does not cause non-Wilsonian hepatic copper toxicosis.". J. Hepatol. 38 (2): 164-8. PMID 12547404. 
  • Tao TY, Liu F, Klomp L, et al. (2004). "The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein.". J. Biol. Chem. 278 (43): 41593-6. doi:10.1074/jbc.C300391200. PMID 12968035. 
  • Klomp AE, van de Sluis B, Klomp LW, Wijmenga C (2004). "The ubiquitously expressed MURR1 protein is absent in canine copper toxicosis.". J. Hepatol. 39 (5): 703-9. PMID 14568250. 
  • Biasio W, Chang T, McIntosh CJ, McDonald FJ (2004). "Identification of Murr1 as a regulator of the human delta epithelial sodium channel.". J. Biol. Chem. 279 (7): 5429-34. doi:10.1074/jbc.M311155200. PMID 14645214. 
  • Ganesh L, Burstein E, Guha-Niyogi A, et al. (2004). "The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes.". Nature 426 (6968): 853-7. doi:10.1038/nature02171. PMID 14685242. 
  • Burstein E, Ganesh L, Dick RD, et al. (2004). "A novel role for XIAP in copper homeostasis through regulation of MURR1.". EMBO J. 23 (1): 244-54. doi:10.1038/sj.emboj.7600031. PMID 14685266. 
  • Stuehler B, Reichert J, Stremmel W, Schaefer M (2005). "Analysis of the human homologue of the canine copper toxicosis gene MURR1 in Wilson disease patients.". J. Mol. Med. 82 (9): 629-34. doi:10.1007/s00109-004-0557-9. PMID 15205742. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Burstein E, Hoberg JE, Wilkinson AS, et al. (2005). "COMMD proteins, a novel family of structural and functional homologs of MURR1.". J. Biol. Chem. 280 (23): 22222-32. doi:10.1074/jbc.M501928200. PMID 15799966. 
  • Coronado VA, Bonneville JA, Nazer H, et al. (2006). "COMMD1 (MURR1) as a candidate in patients with copper storage disease of undefined etiology.". Clin. Genet. 68 (6): 548-51. doi:10.1111/j.1399-0004.2005.00524.x. PMID 16283886. 
  • Zhang Z, Joh K, Yatsuki H, et al. (2006). "Comparative analyses of genomic imprinting and CpG island-methylation in mouse Murr1 and human MURR1 loci revealed a putative imprinting control region in mice.". Gene 366 (1): 77-86. doi:10.1016/j.gene.2005.08.020. PMID 16305817. 
  • de Bie P, van de Sluis B, Burstein E, et al. (2006). "Characterization of COMMD protein-protein interactions in NF-kappaB signalling.". Biochem. J. 398 (1): 63-71. doi:10.1042/BJ20051664. PMID 16573520. 
  • Sommerhalter M, Zhang Y, Rosenzweig AC (2007). "Solution structure of the COMMD1 N-terminal domain.". J. Mol. Biol. 365 (3): 715-21. doi:10.1016/j.jmb.2006.10.030. PMID 17097678. 
  • Maine GN, Mao X, Komarck CM, Burstein E (2007). "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase.". EMBO J. 26 (2): 436-47. doi:10.1038/sj.emboj.7601489. PMID 17183367. 
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