Talk:Coiled coil

From Wikipedia, the free encyclopedia

	MCB Portal This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme.
Start	This article has been rated as Start-Class on the assessment scale.
Mid	This article is on a subject of Mid-importance within molecular and cellular biology.
Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need.

[edit] Representative image and definition of a coiled coil?

Ribbon diagram of 1VCS (model 2), colored from blue (N-terminus) to red (C-terminus).

Hi, I replaced the image of 1VCS with one of a GCN4 leucine zipper, since 1VCS is not a coiled coil, but rather a 3-helix bundle. Coiled coils (as I understand the term) are composed of separate polypeptide chains. You can see more clearly that 1VCS is one polypeptide chain from the figure at the right. But it's possible that I'm mistaken about the definition; what do people here think? Willow 16:36, 8 September 2006 (UTC)

I just looked up the definition of coiled-coil in one of my textboks and it seems that the term is indeed primary used for structures with multiple polypeptide chains. In fact I didn't check of which PDB I create the image from, I just used the same PDB from the previous (rather crappy picture). I wish you would have updated the old picture (which has been there for ages) yesterday and not today, hours after I invest some time to make a new one which is obsolete now... --Splette ^Talk 16:58, 8 September 2006 (UTC)

Hi, Splette, it's nice to meet another person interested in proteins! There's getting to be quite a few of us now, such as Opabinia regalis, Kjaergaard and Tim Vickers (to name those that I've met — I'm sure there are many more). I'm really sorry about my timing on the coiled coil image; I also had noticed the awful ribbon diagram there before, but didn't have the time to fix it until today. :( But I'm sure that I'll have the pleasure of appreciating many contributions from you in the future. Besides, in Wikipedia, nothing is ever truly lost and no effort is in vain. :) Willow 20:18, 8 September 2006 (UTC)