Clonal deletion

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Clonal deletion is a process by which B cells and T cells are deactivated before act significantly upon specific antigens.^[1]

It is one method of immune tolerance.

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• MeSH Clonal+deletion

v • d • e Immune system / Immunology Systems Adaptive immune system vs. Innate immune system • Humoral immune system vs. Cellular immune system • Complement system (Anaphylatoxins) • Intrinsic immune system Antibodies and antigens Antibody (Monoclonal antibodies, Polyclonal antibodies, Autoantibody) • Allotype • Isotype • Idiotype • Antigen (Superantigen) • Polyclonal response Immune cells White blood cells (T cell, B cell, NK cell, Mast cell, Basophil, Eosinophil) • Phagocyte (Neutrophil, Macrophage, Dendritic cell) • Antigen-presenting cell • Reticuloendothelial system Immunity vs. tolerance Immunity • Autoimmunity • Allergy • Tolerance (Central) • Immunodeficiency Immunogenetics Somatic hypermutation • V(D)J recombination • Immunoglobulin class switching • MHC/HLA Substances Cytokines • Opsonin • Cytolysin Other Inflammation • Epitope (Hapten) • Cross-reactivity • Diagnostic immunology