CIZ1

From Wikipedia, the free encyclopedia

CDKN1A interacting zinc finger protein 1

Identifiers

CIZ1; LSFR1; ZNF356

External IDs

MGI: 1920234 HomoloGene: 8112

Gene ontology
Molecular Function:	• nucleic acid binding • zinc ion binding • metal ion binding
Cellular Component:	• intracellular • nucleus
Biological Process:	• regulation of progression through cell cycle

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_012127 (mRNA)
NP_036259 (protein)

NM_028412 (mRNA)
NP_082688 (protein)

Location

Chr 9: 129.97 - 130.01 Mb

Chr 2: 32.19 - 32.2 Mb

Pubmed search

[1]

[2]

CDKN1A interacting zinc finger protein 1, also known as CIZ1, is a human gene.^[1]

[edit] References

^ Entrez Gene: CIZ1 CDKN1A interacting zinc finger protein 1.

[edit] Further reading

Lukasik A, Uniewicz KA, Kulis M, Kozlowski P (2008). "Ciz1, a p21 cip1/Waf1-interacting zinc finger protein and DNA replication factor, is a novel molecular partner for human enhancer of rudimentary homolog.". FEBS J. 275 (2): 332–40. doi:10.1111/j.1742-4658.2007.06203.x. PMID 18081865.
Rahman FA, Ainscough JF, Copeland N, Coverley D (2007). "Cancer-associated missplicing of exon 4 influences the subnuclear distribution of the DNA replication factor CIZ1.". Hum. Mutat. 28 (10): 993–1004. doi:10.1002/humu.20550. PMID 17508423.
den Hollander P, Rayala SK, Coverley D, Kumar R (2006). "Ciz1, a Novel DNA-binding coactivator of the estrogen receptor alpha, confers hypersensitivity to estrogen action.". Cancer Res. 66 (22): 11021–9. doi:10.1158/0008-5472.CAN-06-2336. PMID 17108141.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Coverley D, Marr J, Ainscough J (2005). "Ciz1 promotes mammalian DNA replication.". J. Cell. Sci. 118 (Pt 1): 101–12. doi:10.1242/jcs.01599. PMID 15585571.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Warder DE, Keherly MJ (2004). "Ciz1, Cip1 interacting zinc finger protein 1 binds the consensus DNA sequence ARYSR(0-2)YYAC.". J. Biomed. Sci. 10 (4): 406–17. doi:10.1159/000071160. PMID 12824700.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Mitsui K, Matsumoto A, Ohtsuka S, et al. (1999). "Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1.". Biochem. Biophys. Res. Commun. 264 (2): 457–64. doi:10.1006/bbrc.1999.1516. PMID 10529385.
Gilley J, Fried M (1999). "Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes.". Hum. Mol. Genet. 8 (7): 1313–20. PMID 10369878.