Citrullinase

From Wikipedia, the free encyclopedia

In enzymology, a citrullinase (EC 3.5.1.20) is an enzyme that catalyzes the chemical reaction

L-citrulline + H₂O L-ornithine + CO₂ + NH₃

Thus, the two substrates of this enzyme are L-citrulline and H₂O, whereas its 3 products are L-ornithine, CO₂, and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is L-citrulline N5-carbamoyldihydrolase. Other names in common use include citrulline ureidase, citrulline hydrolase, and L-citrulline 5-N-carbamoyldihydrolase.

[edit] References

• IUBMB entry for 3.5.1.20
• BRENDA references for 3.5.1.20 (Recommended.)
• PubMed references for 3.5.1.20
• PubMed Central references for 3.5.1.20
• Google Scholar references for 3.5.1.20
• Hill DL, Chambers P (1967). "The biosynthesis of proline by Tetrahymena pyriformis". Biochim. Biophys. Acta. 148: 435–47. PMID 6075416. 

[edit] External links

The CAS registry number for this enzyme class is 59088-17-4.

• IUBMB entry for 3.5.1.20

• KEGG entry for 3.5.1.20

• BRENDA entry for 3.5.1.20

• NiceZyme view of 3.5.1.20

• EC2PDB: PDB structures for 3.5.1.20

• PRIAM entry for 3.5.1.20

• PUMA2 entry for 3.5.1.20

• IntEnz: Integrated Enzyme entry for 3.5.1.20

• MetaCyc entry for 3.5.1.20

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047781: citrullinase

• AMIGO entry for GO code 0047781: citrullinase