CIRBP

From Wikipedia, the free encyclopedia

Cold inducible RNA binding protein

PDB rendering based on 1x5s.

Available structures: 1x5s

Identifiers

Symbol(s)

CIRBP; CIRP

External IDs

OMIM: 602649 MGI: 893588 HomoloGene: 980

Gene ontology
Molecular Function:	• nucleotide binding • nucleic acid binding • RNA binding
Cellular Component:	• nucleus
Biological Process:	• response to cold

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001280 (mRNA)
NP_001271 (protein)

XM_986308 (mRNA)
XP_991402 (protein)

Location

Chr 19: 1.22 - 1.22 Mb

Chr 10: 79.57 - 79.57 Mb

Pubmed search

[1]

[2]

Cold inducible RNA binding protein, also known as CIRBP, is a human gene.^[1]

[edit] References

^ Entrez Gene: CIRBP cold inducible RNA binding protein.

[edit] Further reading

Nishiyama H, Itoh K, Kaneko Y, et al. (1997). "A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth.". J. Cell Biol. 137 (4): 899–908. PMID 9151692.
Sheikh MS, Carrier F, Papathanasiou MA, et al. (1997). "Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein.". J. Biol. Chem. 272 (42): 26720–6. PMID 9334257.
Nishiyama H, Danno S, Kaneko Y, et al. (1998). "Decreased expression of cold-inducible RNA-binding protein (CIRP) in male germ cells at elevated temperature.". Am. J. Pathol. 152 (1): 289–96. PMID 9422546.
Nishiyama H, Higashitsuji H, Yokoi H, et al. (1998). "Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene.". Gene 204 (1-2): 115–20. PMID 9434172.
Lee J, Bedford MT (2002). "PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays.". EMBO Rep. 3 (3): 268–73. doi:10.1093/embo-reports/kvf052. PMID 11850402.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Hamid AA, Mandai M, Fujita J, et al. (2004). "Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinoma.". Int. J. Gynecol. Pathol. 22 (3): 240–7. doi:10.1097/01.PGP.0000070851.25718.EC. PMID 12819390.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
Wellmann S, Bührer C, Moderegger E, et al. (2004). "Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism.". J. Cell. Sci. 117 (Pt 9): 1785–94. doi:10.1242/jcs.01026. PMID 15075239.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.