CIC (gene)

From Wikipedia, the free encyclopedia

Capicua homolog (Drosophila)

Identifiers

CIC; KIAA0306

External IDs

MGI: 1918972 HomoloGene: 9031

Gene ontology
Molecular Function:	• DNA binding • protein binding
Cellular Component:	• nucleus
Biological Process:	• regulation of transcription, DNA-dependent

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_015125 (mRNA)
NP_055940 (protein)

NM_027882 (mRNA)
NP_082158 (protein)

Location

Chr 19: 47.48 - 47.49 Mb

Chr 7: 24.98 - 25 Mb

Pubmed search

[1]

[2]

Capicua homolog (Drosophila), also known as CIC, is a human gene.^[1]

[edit] References

^ Entrez Gene: CIC capicua homolog (Drosophila).

[edit] Further reading

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Lee CJ, Chan WI, Scotting PJ (2005). "CIC, a gene involved in cerebellar development and ErbB signaling, is significantly expressed in medulloblastomas.". J. Neurooncol. 73 (2): 101–8. doi:10.1007/s11060-004-4598-2. PMID 15981098.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
Lee CJ, Chan WI, Cheung M, et al. (2003). "CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons.". Brain Res. Mol. Brain Res. 106 (1-2): 151–6. PMID 12393275.
Nagase T, Ishikawa K, Nakajima D, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.". DNA Res. 4 (2): 141–50. PMID 9205841.