Talk:Chromosomal crossover
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Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template) Rated "high" as high school/SAT biology content, part of meiosis and genetic recombination. - tameeria 23:27, 18 February 2007 (UTC) |
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Someone needs to disambiguate this. KirbyMeister 01:36, 10 May 2004 (UTC)
The Idea of crossing over was first proposed by F.A. Janssens. Does anybody know anything more about him? Fawcett5 18:17, 17 January 2006 (UTC)
Yes, that needs to be changed. The cytological basis of crossing over (and even the term "crossing-over") was first described by F.A. Janssens. TH Morgan just used that knowledge to help him expain gene linkage. Morgan postulated that the crossing over (that Janssens had already discovered) created new chromosomal types in a few gametes.
This article should probably be merged with / redirect to genetic recombination. Gringer 03:02, 7 July 2006 (UTC)
- Sorry, after reading Genetic recombination, it makes sense to keep this. The pictures, at least, should be changed to reflect the breakage and rejoining mentioned in the first paragraph, rather than physical twisting of chromosomes. --Gringer 03:12, 7 July 2006 (UTC)
[edit] significance of crossing over
what is its significance can naybody tell me please —The preceding unsigned comment was added by 203.101.182.58 (talk) 11:28, 27 February 2007 (UTC).
[edit] Requested move
Chromosomal crossover → Homologous recombination — Chromosomal crossover is a naturally occurring type of homologous recombination, but homologous recombination also refers to an artificial technique for introducing different DNA sequences into an organism. "Homologous recombination" has been redirecting to "Chromosomal crossover"; rather than create a different page at "Homologous recombination" (which I started to do), I think "Chromosomal crossover" should change name as it is a significant subset homologous recombination. Madeleine 01:17, 18 April 2007 (UTC)
If you really add more information, I think it will be fine to move the page. As it stands, though, the article is only about the natural version, so I can't really support the move at the moment. Dekimasuよ! 03:41, 23 April 2007 (UTC)
- Well, I wasn't comfortable starting to add any information about artificial homologous recombination until this article stood as "homologous recombination", because right now that information does not belong here. But, if that's what is needed to get the move to happen, then I can go ahead and do that. -- Madeleine 04:07, 23 April 2007 (UTC)
It was requested that this article be renamed but there was no consensus for it be moved. --Stemonitis 07:09, 23 April 2007 (UTC)
I strongly feel that homologous recombination should be a separate article. Chromosomal crossover, as described in the first sentence of the current article, occurs during prophase of meiosis. However, as mentioned above, chromosomal crossover is only one type of homologous recombination. There are also other types of natural homologous recombination that would not fit into an article on "chromosomal crossover." For example, homologous recombination is necessary for certain types of DNA repair in eukaryotes and prokaryotes. Another example that could not be included in the current article is the homologous recombination that occurs following introduction of homologous DNA into a bacterium by conjugation, transduction, or natural transformation. If you look at textbooks and research articles, all of these examples are said to occur by homologous recombination, not chromosomal crossover. Therefore, a separate article entitled "homologous recombination" is necessary so that these examples can be described somewhere. At the very least, the current article should be renamed "homologous recombination" so that these other examples can be added. NighthawkJ 18:41, 23 May 2007 (UTC)
- I should have mentioned other types of naturally occurring homologous recombination as well ... I've been intending to create an article for homologous recombination. I had an exchange with User:Jasu, who had created the article Gene_targeting, and he had a draft suggestion you can see if you look at the history for Homologous recombination... but then I never got around do following through. (He felt HR should be a separate article that can mention Chromosomal crossover as a main article, among others).
- Your suggestion here is adding more reasons to do this. I'll try to get it done asap. Madeleine 18:57, 23 May 2007 (UTC)
? isn't this the same as synapsis? 70.246.127.92 20:23, 1 July 2007 (UTC)
[edit] Frequency
The article does not mention how frequently crossover occurs. Not even extreme values are given. Does it happen once in a million times? All the time? Albmont 13:23, 16 November 2007 (UTC) It happens in every cell undergoing meiosis I. —Preceding unsigned comment added by 76.226.94.200 (talk) 20:50, 28 November 2007 (UTC)
In section "Consequences of crossover", it says, " Meiotic recombination allows a more independent selection between the two alleles that occupy the positions of single genes, as recombination shuffles the allele content between sister chromatids." Should it be between non-sister chromatids ? sister chromatids have identical DNA content, so shuffling between them would produce no change ? —Preceding unsigned comment added by 63.82.71.137 (talk) 08:44, 30 November 2007 (UTC)
