Chondroitin 6-sulfotransferase
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In enzymology, a chondroitin 6-sulfotransferase (EC 2.8.2.17) is an enzyme that catalyzes the chemical reaction
- 3'-phosphoadenylyl sulfate + chondroitin
adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate
Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and chondroitin, whereas its two products are adenosine 3',5'-bisphosphate and chondroitin 6'-sulfate.
This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase. Other names in common use include chondroitin 6-O-sulfotransferase, 3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate, sulfotransferase, and terminal 6-sulfotransferase. This enzyme participates in chondroitin sulfate biosynthesis and glycan structures - biosynthesis 1.
[edit] References
- IUBMB entry for 2.8.2.17
- BRENDA references for 2.8.2.17 (Recommended.)
- PubMed references for 2.8.2.17
- PubMed Central references for 2.8.2.17
- Google Scholar references for 2.8.2.17
- Habuchi O, Miyashita N (1982). "Separation and characterization of chondroitin 6-sulfotransferase and chondroitin 4-sulfotransferase from chick embryo cartilage". Biochim. Biophys. Acta. 717: 414–21. PMID 6957247.
[edit] External links
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- The CAS registry number for this enzyme class is 83589-04-2.
[edit] Gene Ontology (GO) codes
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