Chloride potassium symporter

The chloride potassium symporter is a membrane transport protein that is present in the S3-segment of the renal proximal tubule^[1]. It functions in renal chloride reabsorption to transport chloride across the basolateral membrane.^[1]

They can lower intracellular chloride concentrations below the electrochemical equilibrium potential.^[2]

[edit] Types

Types of chloride potassium symporter are:

Each is encoded by a separate gene.

The preceding symporters are actually other types of ion pumps. Member 3, for instance, is the sodium-chloride symporter.

^ ^a ^b Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 780
^ Entrez Gene: SLC12A5 solute carrier family 12, (potassium-chloride transporter) member 5.

This membrane protein-related article is a stub. You can help Wikipedia by expanding it.

v • d • e Membrane transport protein: ion pumps

Symporter, Cotransporter	Na+/K+/2Cl- - Na/Pi3 - Na+/Cl- - Na/glucose - Na+/I- - Cl-/K+ (4, 5)

Antiporter (exchanger)	Na+/H+ - Na+/Ca2+ (Na+/(Ca2+-K+)) - Cl-/HCO3- (Band 3) - Cl-formate exchanger - Cl-oxalate exchanger

ATPase	Cu++ - Ca+ (SERCA-ATP2A2, Plasma membrane) - Na+/K+ - H+/K+ - ATP synthase - H+ (F-type) - H+ (V-type)

Other	Uniporter - Halorhodopsin - Proton pump