Chile number-one hits of 2008
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This is a list of the Top 100 Singles Chart number-ones of 2008.
| Issue Date | Song | Artist |
| January 1 | "Me Enamora" | Juanes |
| January 12 | "Me Enamora" | Juanes |
| January 19 | "Me Enamora" | Juanes |
| January 26 | "Me Enamora" | Juanes |
| February 2 | "Me Enamora" | Juanes |
| February 9 | "Me Enamora" | Juanes |
| February 16 | "Me Enamora" | Juanes |
| February 23 | "Me Enamora" | Juanes |
| March 1[1] | "Me Enamora" | Juanes |
| March 5 | "Sur" | Lucybell [2] |
