Talk:Chemical affinity

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[edit] Pharmacological affinity

How does this concept relate to pharmacological affinity, i.e. The affinity of a chemical for a receptor. I would have thought it was the same but the maths seem completely different. Bilz0r 02:55, 10 September 2007 (UTC)

The short answer is that when a molecule has a chemical attraction to a molecular surface, the movement is quantified by a negative Gibbs free energy and qualified by the word "affinity". A more advanced analysis would use things such as "free energy maps" or model each step in the reaction process in terms of interactions, each being described by an energy of interaction. See: Raffa's 2001 textbook Drug Receptor Thermodynamics to get an idea. --Sadi Carnot 03:16, 27 September 2007 (UTC)

[edit] Review

User:Sadi Carnot has been blocked from editing because of a coordinated effort to insert original research and warped historical interpretations into Wikipedia articles. Chemsitry experts should carefully examine all of the edits by "Sadi Carnot". --JWSchmidt 22:29, 23 October 2007 (UTC)