Chalcone isomerase

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In enzymology, a chalcone isomerase (EC 5.5.1.6) is an enzyme that catalyzes the chemical reaction

a chalcone a flavanone

Hence, this enzyme has one substrate, chalcone, and one product, flavanone.

This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. The systematic name of this enzyme class is flavanone lyase (decyclizing). This enzyme is also called chalcone-flavanone isomerase. This enzyme participates in flavonoid biosynthesis.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1EYP, 1EYQ, 1FM7, 1FM8, 1JEP, 1JX0, and 1JX1.

[edit] References

• IUBMB entry for 5.5.1.6
• BRENDA references for 5.5.1.6 (Recommended.)
• PubMed references for 5.5.1.6
• PubMed Central references for 5.5.1.6
• Google Scholar references for 5.5.1.6
• Moustafa E and Wong E (1967). "Purification and properties of chalcone-flavanone isomerase from soya bean seed". Phytochemistry 6: 625–632. doi:10.1016/S0031-9422(00)86001-X. 

[edit] External links

The CAS registry number for this enzyme class is 9073-57-8.

• IUBMB entry for 5.5.1.6

• KEGG entry for 5.5.1.6

• BRENDA entry for 5.5.1.6

• NiceZyme view of 5.5.1.6

• EC2PDB: PDB structures for 5.5.1.6

• PRIAM entry for 5.5.1.6

• PUMA2 entry for 5.5.1.6

• IntEnz: Integrated Enzyme entry for 5.5.1.6

• MetaCyc entry for 5.5.1.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0045430: chalcone isomerase

• AMIGO entry for GO code 0045430: chalcone isomerase