CFHR5

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Complement factor H-related 5
Identifiers
Symbol(s) CFHR5; CFHL5; FHR-5; FHR5; FLJ10549; MGC133240
External IDs OMIM: 608593 HomoloGene: 57124
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 81494 n/a
Ensembl ENSG00000134389 n/a
Uniprot Q9BXR6 n/a
Refseq NM_030787 (mRNA)
NP_110414 (protein)		 n/a (mRNA)
n/a (protein)
Location Chr 1: 195.21 - 195.25 Mb n/a
Pubmed search [1] n/a

Complement factor H-related 5, also known as CFHR5, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: CFHR5 complement factor H-related 5.

[edit] Further reading

  • McRae JL, Cowan PJ, Power DA, et al. (2001). "Human factor H-related protein 5 (FHR-5). A new complement-associated protein.". J. Biol. Chem. 276 (9): 6747–54. doi:10.1074/jbc.M007495200. PMID 11058592. 
  • Närkiö-Mäkelä M, Hellwage J, Tahkokallio O, Meri S (2001). "Complement-regulator factor H and related proteins in otitis media with effusion.". Clin. Immunol. 100 (1): 118–26. doi:10.1006/clim.2001.5043. PMID 11414752. 
  • Murphy B, Georgiou T, Machet D, et al. (2002). "Factor H-related protein-5: a novel component of human glomerular immune deposits.". Am. J. Kidney Dis. 39 (1): 24–7. PMID 11774097. 
  • McRae JL, Murphy BE, Eyre HJ, et al. (2003). "Location and structure of the human FHR-5 gene.". Genetica 114 (2): 157–61. PMID 12041828. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • McRae JL, Duthy TG, Griggs KM, et al. (2005). "Human factor H-related protein 5 has cofactor activity, inhibits C3 convertase activity, binds heparin and C-reactive protein, and associates with lipoprotein.". J. Immunol. 174 (10): 6250–6. PMID 15879123. 
  • Abrera-Abeleda MA, Nishimura C, Smith JL, et al. (2006). "Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease).". J. Med. Genet. 43 (7): 582–9. doi:10.1136/jmg.2005.038315. PMID 16299065. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Monteferrante G, Brioschi S, Caprioli J, et al. (2007). "Genetic analysis of the complement factor H related 5 gene in haemolytic uraemic syndrome.". Mol. Immunol. 44 (7): 1704–8. doi:10.1016/j.molimm.2006.08.004. PMID 17000000. 
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