CEP110

From Wikipedia, the free encyclopedia


Centrosomal protein 110kDa
Identifiers
Symbol(s) CEP110; FAN; CEP1; bA165P4.1
External IDs OMIM: 605496 HomoloGene: 38260
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 11064 n/a
Ensembl ENSG00000119397 n/a
Refseq NM_007018 (mRNA)
NP_008949 (protein)		 n/a (mRNA)
n/a (protein)
Location Chr 9: 122.88 - 122.98 Mb n/a
Pubmed search [1] n/a

Centrosomal protein 110kDa, also known as CEP110, is a human gene.[1]

This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1.[1]

[edit] References

  1. ^ a b Entrez Gene: CEP110 centrosomal protein 110kDa.

[edit] Further reading

  • Gromley A, Yeaman C, Rosa J, et al. (2005). "Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission.". Cell 123 (1): 75–87. doi:10.1016/j.cell.2005.07.027. PMID 16213214. 
  • Guinn BA, Bland EA, Lodi U, et al. (2005). "Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia.". Biochem. Biophys. Res. Commun. 335 (4): 1293–304. doi:10.1016/j.bbrc.2005.08.024. PMID 16112646. 
  • Jurczyk A, Gromley A, Redick S, et al. (2004). "Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.". J. Cell Biol. 166 (5): 637–43. doi:10.1083/jcb.200405023. PMID 15337773. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gromley A, Jurczyk A, Sillibourne J, et al. (2003). "A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase.". J. Cell Biol. 161 (3): 535–45. doi:10.1083/jcb.200301105. PMID 12732615. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ou YY, Mack GJ, Zhang M, Rattner JB (2002). "CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation.". J. Cell. Sci. 115 (Pt 9): 1825–35. PMID 11956314. 
  • Popovici C, Mattéi MG, Rattner JB, et al. (2000). "Assignment of the centrosomal protein 110 gene (Cep110) to mouse chromosome bands 2B-C1 by in situ hybridization.". Cytogenet. Cell Genet. 89 (3-4): 216–7. PMID 10965126. 
  • Guasch G, Mack GJ, Popovici C, et al. (2000). "FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33).". Blood 95 (5): 1788–96. PMID 10688839. 
  • Osaki E, Nishina Y, Inazawa J, et al. (1999). "Identification of a novel Sry-related gene and its germ cell-specific expression.". Nucleic Acids Res. 27 (12): 2503–10. PMID 10359848. 
  • Schütze S, Machleidt T, Adam D, et al. (1999). "Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling.". J. Biol. Chem. 274 (15): 10203–12. PMID 10187805. 
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548. 
 This article on a gene on chromosome 9 is a stub. You can help Wikipedia by expanding it.