CENPI

From Wikipedia, the free encyclopedia


Centromere protein I
Identifiers
Symbol(s) CENPI; CENP-I; FSHPRH1; LRPR1; Mis6
External IDs OMIM: 300065 MGI: 2147897 HomoloGene: 4899
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 2491 102920
Ensembl ENSG00000102384 ENSMUSG00000031262
Uniprot Q92674 Q3TLU9
Refseq NM_006733 (mRNA)
NP_006724 (protein)		 XM_975916 (mRNA)
XP_981010 (protein)
Location Chr X: 100.24 - 100.31 Mb Chr X: 129.65 - 129.71 Mb
Pubmed search [1] [2]

Centromere protein I, also known as CENPI, is a human gene.[1]

The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis.[1]

[edit] References

  1. ^ a b Entrez Gene: CENPI centromere protein I.

[edit] Further reading

  • Izuta H, Ikeno M, Suzuki N, et al. (2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.". Genes Cells 11 (6): 673–84. doi:10.1111/j.1365-2443.2006.00969.x. PMID 16716197. 
  • Okada M, Cheeseman IM, Hori T, et al. (2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.". Nat. Cell Biol. 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420. 
  • Foltz DR, Jansen LE, Black BE, et al. (2006). "The human CENP-A centromeric nucleosome-associated complex.". Nat. Cell Biol. 8 (5): 458–69. doi:10.1038/ncb1397. PMID 16622419. 
  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220. 
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Obuse C, Yang H, Nozaki N, et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.". Genes Cells 9 (2): 105–20. PMID 15009096. 
  • Liu ST, Hittle JC, Jablonski SA, et al. (2003). "Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis.". Nat. Cell Biol. 5 (4): 341–5. doi:10.1038/ncb953. PMID 12640463. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Roberts RG, Kendall E, Vetrie D, Bobrow M (1997). "Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene.". Genomics 37 (1): 122–4. doi:10.1006/geno.1996.0528. PMID 8921378. 
  • Slegtenhorst-Eegdeman KE, Post M, Baarends WM, et al. (1995). "Regulation of gene expression in Sertoli cells by follicle-stimulating hormone (FSH): cloning and characterization of LRPR1, a primary response gene encoding a leucine-rich protein.". Mol. Cell. Endocrinol. 108 (1-2): 115–24. PMID 7758824. 
  • Adams MD, Dubnick M, Kerlavage AR, et al. (1992). "Sequence identification of 2,375 human brain genes.". Nature 355 (6361): 632–4. doi:10.1038/355632a0. PMID 1538749. 
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