Talk:Cell cycle

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Molecular and Cellular Biology WikiProject This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme.
B This article has been rated as B-Class on the assessment scale.
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high school/SAT biology knowledge and important overview; changed rating from high to top - tameeria 15:12, 18 February 2007 (UTC)

This article was the MCB Collaboration of the Month for the month of August 2007.
For more details, see the MCB Collaboration of the Month history.
To-do list for Cell cycle:

Here are some tasks you can do:


    1. Add more references
    2. Convert textbook references to inline references
    3. Expand Regulation of cell cycle section - Expanded.
    4. Expand Checkpoints section - Ok, probably not necessary as there is Cell cycle checkpoint already
    5. Improve upon / possibly rewrite the lead paragraph - Improved. More work probably needed.
    6. Add diagram(s) to elucidate regulation of cell cycle - Added Image:Regulation of cell cycle.png. Could be improved.
    7. Add section Cell cycle and tumor production - Added section Role of cell cycle in tumor formation; more work needed.

    Contents

    [edit] Article's quality

    Does it describe Eukaryotic cells or all cells ? Do all cells folow this cycle or are there some exceptions ? -- Taw

    I think this is specific only to eucaryotes, but among these, the mechanism is fairly conserved from yeast to man. AttishOculus 22:19, 11 Jun 2005 (UTC)

    Is there a reason to have this article separate from Cell division and Mitosis - Marshman 05:46, 30 Sep 2003 (UTC)

    Yes. Mitosis is only one small part of the cell cycle. There is more than enough information about mitosis to justify its having its own entry, but it should not be combined with cell cycle. ~mdash; Brim 17:38, Nov 27, 2004 (UTC)

    I think this topic would deserve some additional, more detailed information. (exeact transitions, checkpoints, cyclins, CDK's and CKI's in detail etc.) I would be glad to add some more information, regarding the importance of the subject (in cancer research, for example), but as I am only a student, I could use no other source of knowledge but my textbooks, so I would be happy to have an expert look through my work every once in a while.

    Additionally, I fear that stacking up the article with scientific info would make the whole article frightening and overwhelming for non-professionals. What would you recommend in order to avoid that? Would having separate sections in the article after the current one as an introduction be sufficient, or would it be better to add a new article "Cell cycle in detail", or just have a number of new pages linked into the main page (eg. "Replication initiation mechanisms")? What would be the general Wikipedia practice in such cases? AttishOculus 22:19, 11 Jun 2005 (UTC)

    This article lacks so much info...i mean a lot. I came here looking for help on the topic--because i just couldn't understand some of it, and it wasn't here. All of the stages require info of the cell cycle. The Mitosis part deserves its own part. The cycle's checking system needs its own part. This is one bad article. I'll try to fix it in a day or two after my test. :) Nominaladversary 01:54, 31 March 2006 (UTC)

    The mitosis part has its own part at mitosis. I'd bet my boots check points will also direct you to the cycle's checking system too. Aaadddaaammm 07:10, 19 October 2006 (UTC)

    [edit] No description of basic process of cell division

    There has to be a section dvoted to description of all phases during mitosis (and variations during a meiosis). The article seems to dwell heavily upon recent advances in molecular biology. These advances have to be placed in perspective with the general biology of the cell cycle Nattu 20:21, 16 June 2006 (UTC)

    This article is a recent retooling of a rather poor, stubby original. Currently mitosis and meiosis have their own articles, which are in a much better state than this one was; the phases of mitosis also have their own articles. There's an emphasis on molecular biology in the current article because I wrote it :) Feel free to add more general information, as I think in time this article should evolve to be a proper header for Category:Cell cycle.
    Yes, the mol bio part is good and we can shape it further. For now, emphasis must be on cell cycle basics and I will contribute my bit to it. Nattu 19:19, 23 June 2006 (UTC)

    [edit] Image issues

    The current illustration of the cell cycle should be removed or replaced in my opinion. It would almost have been ok if all the phases seemed to have equal duration. But in this illustration S phase is actually smaller than the G2 phase! - HungryHippo 19. july 2006

    You're right, it's not really very good, but I do think it's better than nothing (especially given the explanation of its deficiencies in the caption). I've posted a {{reqdiagram}} in the hopes of attracting a good diagram creator, which I am not. Opabinia regalis 02:07, 20 July 2006 (UTC)

    [edit] About diploid, haploid and monoploid

    "In this quantity of DNA within the cell has increased to 4c, but the cell is still considered diploid." Finally i got the information.

    [edit] embryology

    Does anyone happen to know any embryologists? I think Embryology really needs a lot of expert attention. would sympathtic editors consider a positive vote here? [1]Slrubenstein | Talk 19:05, 28 August 2006 (UTC)


    [edit] Mitosis vs. M phase

    As far as I know M phase=Mitosis+Cytokinesis, but there is no article on M phase, only on Mitosis, and in the picture:

    Schematic of the cell cycle. I=Interphase, M=Mitosis. The duration of mitosis in relation to the other phases has been exaggerated in this diagram
    Schematic of the cell cycle. I=Interphase, M=Mitosis. The duration of mitosis in relation to the other phases has
    been exaggerated in this diagram

    , I think, M phase is denoted by letter "M" and not Mitosis, as there are four phases: G1, S, G2 and M (+G0). Should the text below the picture be changed?

    Andrius 14:49, 29 October 2006 (UTC)

    [edit] About the diagram

    I can make a fairly good diagram, but I am not an exepert on cellulear procesess, so e-mail me with even a napkin drawing of the correct process and I'll "pimp it out". thanks

    Yupi666 20:15, 14 June 2007 (UTC)

    [edit] Copyedit and minor expansion

    I have done some minor expansion and copy-editing and fixed some formatting issues. I will be adding some references in the coming one or two days. Please comment here if there are any errors or omissions. Also, I think it would be better if we do away with the Observation and Research Groups sections. Also, Regulation of cell cycle can be greatly expanded. Or can be made into a totally separate article. Any comments? - TwoOars 10:46, 1 August 2007 (UTC)

    [edit] References

    Added a few references. Am removing the "refs needed" tag. I do not know how to add inline refs though, for the rest of the stuff - I mean the basic stuff about the phases, which is found in any basic textbook. Am assuming inline refs are not needed in such cases. - TwoOars 19:23, 1 August 2007 (UTC)

    [edit] The template

    As an aside, how about adding links to the checkpoints from {{Cell cycle}}? Please comment at Template talk:Cell cycle. Thanks. - TwoOars 18:20, 3 August 2007 (UTC)

    Never mind. Has been taken care of by Arcadian. - TwoOars 17:07, 4 August 2007 (UTC)
    Nobody should be an aside in Wikipedia - feel as free to edit as anybody! Mikael Häggström 16:30, 5 August 2007 (UTC)

    [edit] Another problem with the diagram

    The Yellow "M" should not refer to Metaphase but to mitosis again. The counterpart of interphase is not the metaphase but the mitosis which include prophase, metaphase, anaphase and telophase.—Preceding unsigned comment added by Vardos (talkcontribs)

    You are right. I changed it. I don't know how we missed it all this while, that too after a monthly collaboration. :P - TwoOars (Rev) 16:03, 7 October 2007 (UTC)