CDP-glycerol diphosphatase

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In enzymology, a CDP-glycerol diphosphatase (EC 3.6.1.16) is an enzyme that catalyzes the chemical reaction

CDP-glycerol + H₂O CMP + sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are CDP-glycerol and H₂O, whereas its two products are CMP and sn-glycerol 3-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is CDP-glycerol phosphoglycerohydrolase. Other names in common use include CDP-glycerol pyrophosphatase, and cytidine diphosphoglycerol pyrophosphatase. This enzyme participates in glycerophospholipid metabolism.

[edit] References

• IUBMB entry for 3.6.1.16
• BRENDA references for 3.6.1.16 (Recommended.)
• PubMed references for 3.6.1.16
• PubMed Central references for 3.6.1.16
• Google Scholar references for 3.6.1.16
• GLASER L (1965). "THE SYNTHESIS OF TEICHOIC ACID. IV. ON THE REGULATION OF CYTIDINE 5'-DIPHOSPHATEGLYCEROL CONCENTRATION". Biochim. Biophys. Acta. 101: 6–15. PMID 14329291. 

[edit] External links

The CAS registry number for this enzyme class is 37289-28-4.

• IUBMB entry for 3.6.1.16

• KEGG entry for 3.6.1.16

• BRENDA entry for 3.6.1.16

• NiceZyme view of 3.6.1.16

• EC2PDB: PDB structures for 3.6.1.16

• PRIAM entry for 3.6.1.16

• PUMA2 entry for 3.6.1.16

• IntEnz: Integrated Enzyme entry for 3.6.1.16

• MetaCyc entry for 3.6.1.16

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047734: CDP-glycerol diphosphatase

• AMIGO entry for GO code 0047734: CDP-glycerol diphosphatase