CDP-acylglycerol O-arachidonoyltransferase

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In enzymology, a CDP-acylglycerol O-arachidonoyltransferase (EC 2.3.1.70) is an enzyme that catalyzes the chemical reaction

arachidonoyl-CoA + CDP-acylglycerol CoA + CDP-diacylglycerol

Thus, the two substrates of this enzyme are arachidonoyl-CoA and CDP-acylglycerol, whereas its two products are CoA and CDP-diacylglycerol.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is arachidonoyl-CoA:CDP-acylglycerol O-arachidonoyltransferase. Other names in common use include CDP-acylglycerol O-arachidonyltransferase, and arachidonyl-CoA:CDP-acylglycerol O-arachidonyltransferase. This enzyme participates in glycerophospholipid metabolism.

[edit] References

• IUBMB entry for 2.3.1.70
• BRENDA references for 2.3.1.70 (Recommended.)
• PubMed references for 2.3.1.70
• PubMed Central references for 2.3.1.70
• Google Scholar references for 2.3.1.70
• Thompson W, MacDonald G (1979). "Isolation of a specific arachidonoyl coenzyme A: cytidine diphosphate monoacylglycerol acyltransferase". J. Biol. Chem. 254: 3311–4. PMID 429352. 

[edit] External links

The CAS registry number for this enzyme class is 70771-22-1.

• IUBMB entry for 2.3.1.70

• KEGG entry for 2.3.1.70

• BRENDA entry for 2.3.1.70

• NiceZyme view of 2.3.1.70

• EC2PDB: PDB structures for 2.3.1.70

• PRIAM entry for 2.3.1.70

• PUMA2 entry for 2.3.1.70

• IntEnz: Integrated Enzyme entry for 2.3.1.70

• MetaCyc entry for 2.3.1.70

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047193: CDP-acylglycerol O-arachidonoyltransferase

• AMIGO entry for GO code 0047193: CDP-acylglycerol O-arachidonoyltransferase