CD300C

From Wikipedia, the free encyclopedia

CD300c molecule

Identifiers

CD300C; CMRF-35A; CMRF35; CMRF35A; CMRF35A1; IGSF16; LIR

External IDs

OMIM: 606786 MGI: 3032626 HomoloGene: 74580

Gene ontology
Molecular Function:	• transmembrane receptor activity
Cellular Component:	• integral to plasma membrane • membrane
Biological Process:	• cellular defense response

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_006678 (mRNA)
NP_006669 (protein)

NM_199225 (mRNA)
NP_954695 (protein)

Location

Chr 17: 70.05 - 70.05 Mb

Chr 11: 114.77 - 114.78 Mb

Pubmed search

[1]

[2]

CD300c molecule, also known as CD300C, is a human gene.^[1]

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992).[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: CD300C CD300c molecule.

[edit] Further reading

Clark GJ, Fitzpatrick S, Kuo B, et al. (2003). "CMRF-35A, CMRF-35H: potential new CD.". J. Biol. Regul. Homeost. Agents 16 (3): 233-5. PMID 12456026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Cannon JP, Haire RN, Litman GW (2002). "Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate.". Nat. Immunol. 3 (12): 1200-7. doi:10.1038/ni849. PMID 12415263.
Clark GJ, Cooper B, Fitzpatrick S, et al. (2002). "The gene encoding the immunoregulatory signaling molecule CMRF-35A localized to human chromosome 17 in close proximity to other members of the CMRF-35 family.". Tissue Antigens 57 (5): 415-23. PMID 11556966.
Clark GJ, Green BJ, Hart DN (2000). "The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17.". Tissue Antigens 55 (2): 101-9. PMID 10746781.
Jackson DG, Hart DN, Starling G, Bell JI (1992). "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor.". Eur. J. Immunol. 22 (5): 1157-63. PMID 1349532.