Casopitant

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Casopitant
Systematic (IUPAC) name
(2S,4S)-4-(4-Acetyl-1-piperazinyl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methyl-1-piperidinecarboxamide
Identifiers
CAS number	?
ATC code	?
PubChem	23725089
Chemical data
Formula	C30H35F7N4O2
Mol. mass	616.26 g/mol
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Casopitant (INN) is an neurokinin 1 receptor antagonist undergoing research for the treatment of chemotherapy-induced nausea and vomiting (CINV).^[1] It is developed by GlaxoSmithKline and is likely to be marketed in the US as Rezonic and in the EU as Zunrisa.

[edit] References

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