Casbene synthase

From Wikipedia, the free encyclopedia

In enzymology, a casbene synthase (EC 4.2.3.8) is an enzyme that catalyzes the chemical reaction

geranylgeranyl diphosphate casbene + diphosphate

Hence, this enzyme has one substrate, geranylgeranyl diphosphate, and two products, casbene and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming). Other names in common use include casbene synthetase, and geranylgeranyl-diphosphate diphosphate-lyase (cyclizing). This enzyme participates in diterpenoid biosynthesis.

[edit] References

• IUBMB entry for 4.2.3.8
• BRENDA references for 4.2.3.8 (Recommended.)
• PubMed references for 4.2.3.8
• PubMed Central references for 4.2.3.8
• Google Scholar references for 4.2.3.8
• Moesta P, West CA (1985). "Casbene synthetase: regulation of phytoalexin biosynthesis in Ricinus communis L. seedlings. Purification of casbene synthetase and regulation of its biosynthesis during elicitation". Arch. Biochem. Biophys. 238: 325–33. PMID 3985625. 

[edit] External links

The CAS registry number for this enzyme class is 69106-45-2.

• IUBMB entry for 4.2.3.8

• KEGG entry for 4.2.3.8

• BRENDA entry for 4.2.3.8

• NiceZyme view of 4.2.3.8

• EC2PDB: PDB structures for 4.2.3.8

• PRIAM entry for 4.2.3.8

• PUMA2 entry for 4.2.3.8

• IntEnz: Integrated Enzyme entry for 4.2.3.8

• MetaCyc entry for 4.2.3.8

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050449: casbene synthase

• AMIGO entry for GO code 0050449: casbene synthase