Cartilage-derived angiogenesis inhibitor
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A cartilage-derived angiogenesis inhibitor is an angiogenesis inhibitor produced from cartilage. Examples include the peptide troponin I[1] and chondromodulin I[2].
The antiangiogenic effect may be an inhibition of basement membrane degradation.
[edit] References
- ^ Kern BE, Balcom JH, Antoniu BA, Warshaw AL, Fernández-del Castillo C (2003). "Troponin I peptide (Glu94-Leu123), a cartilage-derived angiogenesis inhibitor: in vitro and in vivo effects on human endothelial cells and on pancreatic cancer". J. Gastrointest. Surg. 7 (8): 961–8; discussion 969. PMID 14675705.
- ^ Suppression of T Cell Responses by Chondromodulin I, a. Cartilage-Derived Angiogenesis Inhibitory Factor. Therapeutic Potential in Rheumatoid Arthritis ...
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