Carnosine N-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a carnosine N-methyltransferase (EC 2.1.1.22) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + carnosine S-adenosyl-L-homocysteine + anserine

Thus, the two substrates of this enzyme are S-adenosyl methionine and carnosine, whereas its two products are S-adenosylhomocysteine and anserine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:carnosine N-methyltransferase. This enzyme participates in histidine metabolism.

[edit] References

• IUBMB entry for 2.1.1.22
• BRENDA references for 2.1.1.22 (Recommended.)
• PubMed references for 2.1.1.22
• PubMed Central references for 2.1.1.22
• Google Scholar references for 2.1.1.22
• McManus IR (1962). "Enzymatic synthesis of anserine in skeletal muscle by N-methylation of carnosine". J. Biol. Chem. 237: 1207–1211. 

[edit] External links

The CAS registry number for this enzyme class is 37256-93-2.

• IUBMB entry for 2.1.1.22

• KEGG entry for 2.1.1.22

• BRENDA entry for 2.1.1.22

• NiceZyme view of 2.1.1.22

• EC2PDB: PDB structures for 2.1.1.22

• PRIAM entry for 2.1.1.22

• PUMA2 entry for 2.1.1.22

• IntEnz: Integrated Enzyme entry for 2.1.1.22

• MetaCyc entry for 2.1.1.22

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030735: carnosine N-methyltransferase

• AMIGO entry for GO code 0030735: carnosine N-methyltransferase