Carnitine decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, a carnitine decarboxylase (EC 4.1.1.42) is an enzyme that catalyzes the chemical reaction

carnitine 2-methylcholine + CO₂

Hence, this enzyme has one substrate, carnitine, and two products, 2-methylcholine and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is carnitine carboxy-lyase (2-methylcholine-forming). This enzyme is also called carnitine carboxy-lyase. It employs one cofactor, ATP.

[edit] References

• IUBMB entry for 4.1.1.42
• BRENDA references for 4.1.1.42 (Recommended.)
• PubMed references for 4.1.1.42
• PubMed Central references for 4.1.1.42
• Google Scholar references for 4.1.1.42
• Khairallah EA, Wolf G (1967). "Carnitine decarboxylase. The conversion of carnitine to beta-methylcholine". J. Biol. Chem. 242: 32–9. PMID 6016331. 

[edit] External links

The CAS registry number for this enzyme class is 37237-38-0.

• IUBMB entry for 4.1.1.42

• KEGG entry for 4.1.1.42

• BRENDA entry for 4.1.1.42

• NiceZyme view of 4.1.1.42

• EC2PDB: PDB structures for 4.1.1.42

• PRIAM entry for 4.1.1.42

• PUMA2 entry for 4.1.1.42

• IntEnz: Integrated Enzyme entry for 4.1.1.42

• MetaCyc entry for 4.1.1.42

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047729: carnitine decarboxylase

• AMIGO entry for GO code 0047729: carnitine decarboxylase