Carboxymethyloxysuccinate lyase

From Wikipedia, the free encyclopedia

In enzymology, a carboxymethyloxysuccinate lyase (EC 4.2.99.12) is an enzyme that catalyzes the chemical reaction

carboxymethyloxysuccinate fumarate + glycolate

Hence, this enzyme has one substrate, carboxymethyloxysuccinate, and two products, fumarate and glycolate.

This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that cleave carbon-oxygen bonds. The systematic name of this enzyme class is carboxymethyloxysuccinate glycolate-lyase (fumarate-forming). Other names in common use include carbon-oxygen lyase, and carboxymethyloxysuccinate glycolate-lyase.

[edit] References

• IUBMB entry for 4.2.99.12
• BRENDA references for 4.2.99.12 (Recommended.)
• PubMed references for 4.2.99.12
• PubMed Central references for 4.2.99.12
• Google Scholar references for 4.2.99.12
• Peterson D, Llaneza J (1974). "Identification of a carbon-oxygen lyase activity cleaving the ether linkage in carboxymethyloxysuccinic acid". Arch. Biochem. Biophys. 162: 135–46. PMID 4831330. 

[edit] External links

The CAS registry number for this enzyme class is 53167-89-8.

• IUBMB entry for 4.2.99.12

• KEGG entry for 4.2.99.12

• BRENDA entry for 4.2.99.12

• NiceZyme view of 4.2.99.12

• EC2PDB: PDB structures for 4.2.99.12

• PRIAM entry for 4.2.99.12

• PUMA2 entry for 4.2.99.12

• IntEnz: Integrated Enzyme entry for 4.2.99.12

• MetaCyc entry for 4.2.99.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047772: carboxymethyloxysuccinate lyase

• AMIGO entry for GO code 0047772: carboxymethyloxysuccinate lyase