Carbarsone
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Carbarsone
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| Systematic (IUPAC) name | |
| [4-(Carbamoylamino)phenyl]arsonic acid | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C7H9AsN2O4 |
| Mol. mass | 260.079 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Oral |
Carbarsone is an arsenic-based antiprotozoal drug which has been used in the treatment of amebiasis and other infections.[1][2][3] It was available for use in the United States as a drug for amebiasis as late as 1991. Thereafter, it remained available as an additive for turkey feed for improving weight and controlling Blackhead disease.[4][5]
[edit] References
- ^ SASAKI T, YOKAGAWA M, WYKOFF DE, RITICHIE LS (1956). "Asymptomatic amebiasis; treatment with atabrine in combination with carbarsone or chiniofon". United States Armed Forces medical journal 7 (3): 363–8. PMID 13299463.
- ^ RADKE RA (1955). "Ameboma of the intestine: an analysis of the disease as presented in 78 collected and 41 previously unreported cases". Ann. Intern. Med. 43 (5): 1048–66. PMID 13268997.
- ^ HOEKENGA MT (1951). "A comparison of aureomycin and carbarsone in the treatment of intestinal amebiasis". Am. J. Trop. Med. Hyg. 31 (4): 423–5. PMID 14857246.
- ^ McDougald LR (1979). "Efficacy and compatibility of amprolium and carbarsone against Coccidiosis and blackhead in turkeys". Poult. Sci. 58 (1): 76–80. PMID 572970.
- ^ Worden AN, Wood EC (1973). "The effect of Carbarsone (33.6 per cent w-v p-ureidobenzene arsonic acid) on bodyweight gain, food conversion and tissue arsenic levels of turkey poults". J. Sci. Food Agric. 24 (1): 35–41. PMID 4696593.
