Calponin

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calponin 1, basic, smooth muscle
Identifiers
Symbol	CNN1
Entrez	1264
HUGO	2155
OMIM	600806
RefSeq	NM_001299
UniProt	P51911
Other data
Locus	Chr. 19 p13.2-13.1

calponin 2
Identifiers
Symbol	CNN2
Entrez	1265
HUGO	2156
OMIM	602373
RefSeq	NM_004368
UniProt	Q99439
Other data
Locus	Chr. 21 q11.1

calponin 3, acidic
Identifiers
Symbol	CNN3
Entrez	1266
HUGO	2157
OMIM	602374
RefSeq	NM_001839
UniProt	Q6FHA7
Other data
Locus	Chr. 1 p22-p21

Calponin is a calcium binding protein. Calponin tonically inhibits the ATPase activity of myosin in smooth muscle. Phosphorylation of calponin by a protein kinase (which is dependent upon Calcium binding to calmodulin) releases the calponin's inhibition of the smooth muscle ATPase.