Calligonine
From Wikipedia, the free encyclopedia
| Calligonine | |
|---|---|
| IUPAC name | (1R)-1-methyl-2,3,4,9-tetrahydro-
1H-pyrido[3,4-b]indole |
| Other names | Elaeagnine, tetrahydroharman(e) |
| Identifiers | |
| CAS number | [2254-36-6] |
| PubChem | |
| SMILES | c13ccccc1nc2c3CCNC2C |
| Properties | |
| Molecular formula | C12H14N2 |
| Molar mass | 186.25296 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
|
Calligonine, an isomer of tetrahydroharman, is a major alkaloid constituent of the roots of Calligonum minimum and the bark of Elaeagnus augustifolia. When taken internally, it has the effect of substantially lowering blood pressure for an extended period of time, similar to reserpine.
[edit] References
- Harborne, Jeffrey B.; Herbert Baxter and Gerard Moss (1999). Phytochemical Dictionary: A Handbook of Bioactive Compounds from Plants, 2, CRC Press, 195. ISBN 0748406204.
- Kar, Ashutosh. Pharmacognosy and Pharmacobiotechnology. New Age Publishers, 580. ISBN 8122415016.

