Calligonine

From Wikipedia, the free encyclopedia

Calligonine
IUPAC name (1R)-1-methyl-2,3,4,9-tetrahydro-

1H-pyrido[3,4-b]indole

Other names Elaeagnine, tetrahydroharman(e)
Identifiers
CAS number [2254-36-6]
PubChem 442025
SMILES c13ccccc1nc2c3CCNC2C
Properties
Molecular formula C12H14N2
Molar mass 186.25296 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Calligonine, an isomer of tetrahydroharman, is a major alkaloid constituent of the roots of Calligonum minimum and the bark of Elaeagnus augustifolia. When taken internally, it has the effect of substantially lowering blood pressure for an extended period of time, similar to reserpine.

[edit] References

  • Harborne, Jeffrey B.; Herbert Baxter and Gerard Moss (1999). Phytochemical Dictionary: A Handbook of Bioactive Compounds from Plants, 2, CRC Press, 195. ISBN 0748406204. 
  • Kar, Ashutosh. Pharmacognosy and Pharmacobiotechnology. New Age Publishers, 580. ISBN 8122415016.