Butyrate kinase

From Wikipedia, the free encyclopedia

In enzymology, a butyrate kinase (EC 2.7.2.7) is an enzyme that catalyzes the chemical reaction

ATP + butanoate ADP + butanoyl phosphate

Thus, the two substrates of this enzyme are ATP and butanoate, whereas its two products are ADP and butanoyl phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:butanoate 1-phosphotransferase. This enzyme participates in butanoate metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1SAZ and 1X9J.

[edit] References

• IUBMB entry for 2.7.2.7
• BRENDA references for 2.7.2.7 (Recommended.)
• PubMed references for 2.7.2.7
• PubMed Central references for 2.7.2.7
• Google Scholar references for 2.7.2.7
• Hartmanis MG (1987). "Butyrate kinase from Clostridium acetobutylicum". J. Biol. Chem. 262: 617–21. PMID 3027059. 
• Twarog R and Wolfe RS (1962). "Enzymatic phosphorylation of butyrate". J. Biol. Chem. 237: 2474–2477. 

[edit] External links

The CAS registry number for this enzyme class is 37278-14-1.

• IUBMB entry for 2.7.2.7

• KEGG entry for 2.7.2.7

• BRENDA entry for 2.7.2.7

• NiceZyme view of 2.7.2.7

• EC2PDB: PDB structures for 2.7.2.7

• PRIAM entry for 2.7.2.7

• PUMA2 entry for 2.7.2.7

• IntEnz: Integrated Enzyme entry for 2.7.2.7

• MetaCyc entry for 2.7.2.7

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047761: butyrate kinase

• AMIGO entry for GO code 0047761: butyrate kinase