Talk:Buspirone
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This article may be too technical for a general audience. Please help improve this article by providing more context and better explanations of technical details to make it more accessible, without removing technical details. |
"^ Lilja, JJ; Kivisto KT, Backman JT, Lamberg TS, Neuvonen PJ (December 1998). "Grapefruit juice substantially increases plasma concentrations of buspirone Do not mix the pills in grapefruit juice. Resulting so would be in euphoria". Clin Pharmacol Ther 64 (6): 655-660." What euphoria?! Who added that ?! Original research doesn't mention any of that! Please confirm. Or delete. Spacehead84 (talk) 09:43, 18 April 2008 (UTC)
This article may need a total revamp because it has just come to my attention that the latest drug bibles for gps in the UK (I have just seen my gp to try get some buspirone) are now listing buspirone as a benzodiazepine. This is a potentially serious issue within this article as those reading it thinking the drug is without risk in terms of addiction/side effects/contraindications may be at risk of benzo type problems if indeed the bible is right. —Preceding unsigned comment added by 129.12.237.236 (talk) 12:23, 1 April 2008 (UTC)
1. but it has an efficacy comparable to diazepam in treating generalized anxiety disorder
2. Generally, buspirone works less well than benzodiazepines (diazepam, principle item)
????
The information age is vastly overrated... But people are not aware of this. The end is near —Preceding unsigned comment added by Cisum.ili.dilm (talk • contribs) 15:33, 7 November 2007 (UTC)
BuSpar made me very drowsy (almost passing out at times). It also did nothing at all for my GAD. I have read on other sites that it works well with an SSRI but doesn't work well by itself. I haven't tried it with an SSRI but I can attest that it does nothing by itself. The makers toute this drug as being non-drowsy, however, I have fallen asleep standing up while on this drug, and I'm a poor sleeper!
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[edit] Buspar
I have moderate GAD. I started taking Buspar 2.5 years ago. I am amazed at how well this drug works. It makes me dizzy about 30 minutes after I take it. The feeling lasts only for about an hour. I get very sleepy from the drug. I take my first dose early in the morning and fall back to sleep. I take my second dose before I fall asleep in the night. Thank the good Lord that this drug works!
buspar didnt make me sleepy and really hasn't done anything with by general anxiety disorder. i also take zoloft but nothing seems to help. Can someone relate.
I just started taking Buspar today. I also take Cymbalta and Clonazepam, both at max dosage levels and still have anxiety problems. The psychiatrist told me that the Buspar can help to increase the effectiveness of the other anxiety and depression meds I am on as well as provide some extra kick. Remember everyone, I have been through the worst and back with this disease, it is a constant excercise in trial and error to find the right mix of medications that work for you. Keep trying, and keep talking to your doctor. Constantly reporting changes in your symptoms really helps the doctor and increases your chances of finding the right combination of drugs for your condition.
I have been taking Buspar for one month. It has not helped my general anxiety as I had hoped, if at all, but I like it for other reasons. 1) it helps with social anxiety. I tend to be shy and get anxious in social situations and now this is not as much as a problem for me. 2) it gives me an energy boost each day. I am more productive at work and less tired. Sometimes it causes me to be too hyper and manic and I can't get to sleep and am bouncing off the walls, but this is improving with time. It certainly does not cause me to be sleepy or sedated. 3) it helps me stick on task and get projects done I was formerly unable to. It seems to increase my ability to concentrate. 4) it seems to improve/lighten my mood. 5) it enhances my senses of smell and taste. This is decreasing with time on the drug, but the first week, this was very pronounced and I really liked it. Now I experience this usually just within the first hour or so of a dose. 6) it seems to enhance my pleasure when doing things that are normally pleasurable. Now they are more so. 7) in the first few days on the drug, I became a very reckless driver. Completely unlike me. So beware. Now this effect is gone. Overall, with time, a number of these effects are decreasing. The main ones that remain for me are decreased social anxiety, increased energy, and lightening of mood.
This paragraph is from another user. I found this drug worked immediately and very well for anxiety, but in me it also produced profound insomnia (I did not sleep for 48 hours) and so I discontinued it pretty quickly. It also enhanced my sense of smell, which I enjoyed. Although I was unable to continue with the drug, I think it gets an undeserved bad rap as "useless for anxiety" - that was definitely not my experience. 24.58.172.158 (talk) 02:55, 7 January 2008 (UTC)
[edit] comparison to diazepam
it may be misleading to compare this drug to valium or any other benzo. it obviously does not function in the same way, since dependency would result if it did. thus the experience induced by buspirone is going to differ from that of valium. perhaps this is why there is no citation for the comparison.
(i have a lot of experience with both substances and other anti-anxiety drugs). —The preceding unsigned comment was added by Harlequence (talk • contribs) 06:17, 17 January 2007 (UTC).
See the citations I added; studies showing comparable efficacy between diazepam and buspirone. Arcane63 15:28, 16 March 2007 (UTC)
[edit] decline?
"Its sales have been on the decline in recent years due to its unpleasant side effects."
This claim sounds strange to me. Other sources consider it to be a drug with exceptionally low side effects! Are sales really declining? If so, what are the reasons? Ineffectiveness? lack of incentive to promote it because of patent expiration? Definitely [citation needed]!
[edit] Fair use rationale for Image:BusparAd.png
Image:BusparAd.png is being used on this article. I notice the image page specifies that the image is being used under fair use but there is no explanation or rationale as to why its use in this Wikipedia article constitutes fair use. In addition to the boilerplate fair use template, you must also write out on the image description page a specific explanation or rationale for why using this image in each article is consistent with fair use.
Please go to the image description page and edit it to include a fair use rationale. Using one of the templates at Wikipedia:Fair use rationale guideline is an easy way to insure that your image is in compliance with Wikipedia policy, but remember that you must complete the template. Do not simply insert a blank template on an image page.
If there is other fair use media, consider checking that you have specified the fair use rationale on the other images used on this page. Note that any fair use images uploaded after 4 May, 2006, and lacking such an explanation will be deleted one week after they have been uploaded, as described on criteria for speedy deletion. If you have any questions please ask them at the Media copyright questions page. Thank you.
BetacommandBot 06:56, 27 October 2007 (UTC)
[edit] "Brain zaps"
Paresthesia is listed under side-effects, but not "brain zaps," which is similar but clinically different. I know from personal experience that the so-called brain zaps are definitely a side-effect of taking Buspar. Would anyone object to adding "brain zaps" in parentheses following paresthesia in the list of side-effects? Svadhisthana (talk) 18:36, 28 January 2008 (UTC)
