BRD3

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Bromodomain containing 3
PDB rendering based on 2nxb.
Available structures: 2nxb, 2oo1
Identifiers
Symbol(s) BRD3; KIAA0043; ORFX; RING3L
External IDs OMIM: 601541 MGI: 1914632 HomoloGene: 81801
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 8019 67382
Ensembl ENSG00000169925 ENSMUSG00000026918
Uniprot Q15059 Q05DR7
Refseq NM_007371 (mRNA)
NP_031397 (protein)		 NM_023336 (mRNA)
NP_075825 (protein)
Location Chr 9: 135.89 - 135.92 Mb Chr 2: 27.27 - 27.3 Mb
Pubmed search [1] [2]

Bromodomain containing 3, also known as BRD3, is a human gene.[1]

This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.[1]

[edit] References

  1. ^ a b Entrez Gene: BRD3 bromodomain containing 3.

[edit] Further reading

  • Nomura N, Nagase T, Miyajima N, et al. (1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 1 (5): 223-9. PMID 7584044. 
  • Thorpe KL, Abdulla S, Kaufman J, et al. (1996). "Phylogeny and structure of the RING3 gene.". Immunogenetics 44 (5): 391-6. PMID 8781126. 
  • Thorpe KL, Gorman P, Thomas C, et al. (1997). "Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene.". Gene 200 (1-2): 177-83. PMID 9373153. 
  • Kaneko H, Inoue R, Teramoto T, et al. (2003). "Detection of the genes induced in activated lymphocytes by modified differential display.". Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología 12 (2): 86-90. PMID 12371535. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Zhou M, Peng C, Nie XM, et al. (2003). "[Expression of BRD7-interacting proteins,BRD2 and BRD3, in nasopharyngeal carcinoma tissues]". Ai Zheng 22 (2): 123-7. PMID 12600283. 
  • Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369-74. doi:10.1038/nature02465. PMID 15164053. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ishii H, Mimori K, Mori M, Vecchione A (2005). "Differentially expressed genes in endothelial differentiation.". DNA Cell Biol. 24 (7): 432-7. doi:10.1089/dna.2005.24.432. PMID 16008511. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
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