Talk:BRCA2
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Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template) It is good that at least a stub is present on the BRCA genes. However, it would be best if both of these were extensively modified. As a first pass, I'd like to see the following: 1. Differential between genetic/familial breast csncers in age of onset (BRCA mutations are far more common in early onset disease) 2. Discussion of associated risks including recurrence on the other side, risks to males carrying mutations, and risks to first degree relatives. 3. Discussion of other cancers at increased risk in BRCA mutaion carriers 4. discussion of differences in clinical presentation of BRCA1 vs BRCA2 carriers 5. Increased prevalence of mutations in Ashkenazi jews This is not my specific field, and it would be great for a specialist to edit these. |
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Some text in this article was originally taken from http://ghr.nlm.nih.gov/gene=brca2 (public domain)
