Branched-chain-fatty-acid kinase

From Wikipedia, the free encyclopedia

In enzymology, a branched-chain-fatty-acid kinase (EC 2.7.2.14) is an enzyme that catalyzes the chemical reaction

ATP + 2-methylpropanoate ADP + 2-methylpropanoyl phosphate

Thus, the two substrates of this enzyme are ATP and 2-methylpropanoate, whereas its two products are ADP and 2-methylpropanoyl phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:branched-chain-fatty-acid 1-phosphotransferase. This enzyme is also called isobutyrate kinase.

[edit] References

• IUBMB entry for 2.7.2.14
• BRENDA references for 2.7.2.14 (Recommended.)
• PubMed references for 2.7.2.14
• PubMed Central references for 2.7.2.14
• Google Scholar references for 2.7.2.14
• Harwood CS, Canale-Parola E (1982). "Properties of acetate kinase isozymes and a branched-chain fatty acid kinase from a spirochete". J. Bacteriol. 152: 246–54. PMID 6288660. 

[edit] External links

The CAS registry number for this enzyme class is 84177-54-8.

• IUBMB entry for 2.7.2.14

• KEGG entry for 2.7.2.14

• BRENDA entry for 2.7.2.14

• NiceZyme view of 2.7.2.14

• EC2PDB: PDB structures for 2.7.2.14

• PRIAM entry for 2.7.2.14

• PUMA2 entry for 2.7.2.14

• IntEnz: Integrated Enzyme entry for 2.7.2.14

• MetaCyc entry for 2.7.2.14

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047758: branched-chain fatty acid kinase

• AMIGO entry for GO code 0047758: branched-chain fatty acid kinase