Blue-light hazard

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Blue-light hazard is defined as the potential for a photochemical induced retinal injury resulting from radiation exposure at wavelengths primarily between 400 nm and 500 nm,[1]. The mechanisms for photochemical induced retinal injury are caused by the absorption of light by photoreceptors in the eye. Under normal conditions when light hits a photoreceptor, the cell bleaches and becomes useless until it has recovered through a metabolic process called the “visual cycle.” [2][3] Absorption of blue light, however, has been shown to cause a reversal of the process where cells become unbleached and responsive again to light before it is ready. This greatly increases the potential for oxidative damage[4]. By this mechanism, some biological tissues such as skin, the lens of the eye, and in particular the retina may show irreversible changes induced by prolonged exposure to moderate levels of UV radiation and short-wavelength light.[citation needed]

[edit] References

  1. ^ American National Standard Institute/ Illuminating Engineering Society of North America. “ANSI/IESNA RP-27.1-05: Recommended Practice for Photobiological Safety for Lamp and Lamp Systems – General Requirements.” Illuminating Engineering Society of North America Web Store 10 June. 2007 <https://www.iesna.org/shop/>.
  2. ^ (Williams TP, Howell WL. Action spectrum of retinal light-damage in albino rats. Invest Ophthalmol Vis Sci 1983;24:285–7.
  3. ^ Pautler EL, Morita M, Beezley D. Hemoprotein(s) mediate blue light damage in the retinal pigment epithelium. Photochem Photobiol 1990;51:599–605.
  4. ^ Grimm C, et al. Rhodopsin-Mediated Blue-Light Dam age to the rat Retina: Effect of Photoreversal of Bleaching. Invest Ophthalmol Vis Sci 2001 Feb;42(2):497-50.