Bis-tris methane
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| Bis-tris methane | |
|---|---|
 |
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| IUPAC name | 2-[Bis-(2-hydroxyethyl)-amino]- 2-hydroxymethyl-propane-1,3-diol |
| Other names | Bis-tris Bis-(2-hydroxy-ethyl)- |
| Identifiers | |
| CAS number | [6976-37-0] |
| RTECS number | TY2900000 |
| SMILES | OCC(CO)(N(CCO)CCO)CO |
| Properties | |
| Molecular formula | C8H19NO5 |
| Molar mass | 209.2418 g/mol |
| Appearance | white crystalline powder |
| Density | ? g/l, solid (25°C) |
| Melting point |
102-106°C (375-379K) |
| Boiling point |
(?K) |
| Solubility in water | 67? g/100 ml (20°C) |
| Acidity (pKa) | 5.80-7.30 @25°C |
| Hazards | |
| MSDS | External MSDS |
| Main hazards | Irritant. |
| NFPA 704 |
 0
2
0
|
| R-phrases | R36, R37, R38. |
| S-phrases | S26, S36. |
| Flash point | Non-flammable. |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Bis-tris is an abbreviation of the trivial name (Bis(2-hydroxyethyl)-imino-tris(hydroxymethyl)-methane) for 2-[Bis(2-hydroxyethyl)imino]-2-(hydroxymethyl)-1,3-propanediol. It is generally used as a buffering agent in biochemistry. Bis-tris is an organic tertiary amine with labile protons having a pKa of 6.46 at 25°C. It is an effective buffer between the pH 5.8 and 7.3.
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