Benzamide

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Benzamide

IUPAC name	Benzamide
Other names	Benzoic acid amide, Phenyl carboxamide, Benzoylamide
Identifiers
CAS number	[55-21-0]
PubChem	2331
EINECS number	200-227-7
RTECS number	CU8700000
SMILES	C1=CC=C(C=C1)C(=O)N
InChI	1/C7H7NO/c8-7(9)6-4-2-1- 3-5-6/h1-5H,(H2,8,9)/f/h8H2
Properties
Molecular formula	C₇H₇NO
Molar mass	121.14 g/mol
Appearance	Off-white solid
Density	1.341 g/cm³
Melting point	127 - 130 °C
Boiling point	288 °C
Solubility in water	13 g/l pKa in DMSO = 23.35
Hazards
EU classification	Harmful (Xn)
NFPA 704	1 1 0
R-phrases	R22, R40
S-phrases	S36/37/39
Flash point	180 °C
Autoignition temperature	> 500 °C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Benzamide is an off-white solid with the chemical formula of C₆H₅CONH₂. It is a derivative of benzoic acid. It is slightly soluble in water, and soluble in many organic solvents.

[edit] Benzamides

Amisulpride - a substituted benzamide

Benzamides are a class of amides of benzoic acid. In psychiatry some substituted benzamides are therapeutically used as neuroleptics and/or antipsychotics. Two active substances from the group of benzamides are in use:

Another benzamide, Remoxipride, was taken off the market in 1993 because of life-threatening side effects. Some analgetics like salicylamide or ethenzamide also have benzamide structures.