Image:Bcr abl sti.jpg

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Crystal Structure Of The C-Abl Kinase Domain In Complex With Sti-571 ( Imatinib mesylate).

Structure file downloaded from RCSB (public domain) and rendered with RasMol by me. Use as you wish.

Title: Crystal Structure Of The C-Abl Kinase Domain In Complex With Sti-571. Compound: Mol_Id: 1; Molecule: Proto-Oncogene Tyrosine-Protein Kinase Abl; Chain: A, B; Fragment: Kinase Domain; Synonym: P150, C-Abl; Ec: 2.7.1.112; Engineered: Yes Authors: B. Nagar, W. Bornmann, T. Schindler, B. Clarkson, J. Kuriyan Exp. Method: X-ray Diffraction Classification: Transferase EC Number: 2.7.1.112 (Protein-tyrosine kinase) Go to IUBMB EC entry Source: Mus musculus Go to NCBI Taxonomy entry Primary Citation: Nagar, B., Bornmann, W., Pellicena, P., Schindler, T., Veach, D. R., Miller, W. T., Clarkson, B., Kuriyan, J.: Crystal Structures of the Kinase Domain of C-Abl in Complex with the Small Molecule Inhibitors Pd173955 and Imatinib (Sti-571) Cancer Res. 62 pp. 4236 (2002)

[edit] Links

http://www.rcsb.org

http://www.rcsb.org/pdb/cgi/explore.cgi?job=summary&pdbId=1IEP&page=0&pid=7891116633807

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current00:24, 21 May 2005865×716 (76 KB)Mxpule (Talk | contribs) (Crystal Structure Of The C-Abl Kinase Domain In Complex With Sti-571. Structure file downloaded from RCSB (public domain) and rendered with rasmol by me. Use as you wish. Title: Crystal Structure Of The C-Abl Kinase Domain In Complex With Sti-571)

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