BANP
From Wikipedia, the free encyclopedia
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BTG3 associated nuclear protein
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| Identifiers | |||||
| Symbol(s) | BANP; DKFZp761H172; FLJ10177; FLJ20538; SMAR1; SMARBP1 | ||||
| External IDs | MGI: 1889023 HomoloGene: 9635 | ||||
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| Orthologs | |||||
| Human | Mouse | ||||
| Entrez | 54971 | 53325 | |||
| Ensembl | n/a | ENSMUSG00000025316 | |||
| Refseq | NM_017869 (mRNA) NP_060339 (protein) |
NM_016812 (mRNA) NP_058092 (protein) |
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| Location | n/a | Chr 8: 124.84 - 124.91 Mb | |||
| Pubmed search | [1] | [2] | |||
BTG3 associated nuclear protein, also known as BANP, is a human gene.[1]
This gene encodes a protein that binds to matrix attachment regions. The protein functions as a tumor suppressor and cell cycle regulator. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[1]
[edit] References
[edit] Further reading
- Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807–28. PMID 8889549.
- Birot A, Duret L, Bartholin L, et al. (2000). "Identification and molecular analysis of BANP.". Gene 253 (2): 189–96. PMID 10940556.
- Chattopadhyay S, Kaul R, Charest A, et al. (2001). "SMAR1, a novel, alternatively spliced gene product, binds the Scaffold/Matrix-associated region at the T cell receptor beta locus.". Genomics 68 (1): 93–6. doi:. PMID 10950932.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Kaul R, Mukherjee S, Ahmed F, et al. (2003). "Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice.". Int. J. Cancer 103 (5): 606–15. doi:. PMID 12494467.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:. PMID 14702039.
- Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:. PMID 15146197.
- Kaul-Ghanekar R, Jalota A, Pavithra L, et al. (2004). "SMAR1 and Cux/CDP modulate chromatin and act as negative regulators of the TCRbeta enhancer (Ebeta).". Nucleic Acids Res. 32 (16): 4862–75. doi:. PMID 15371550.
- Kaul-Ghanekar R, Majumdar S, Jalota A, et al. (2005). "Abnormal V(D)J recombination of T cell receptor beta locus in SMAR1 transgenic mice.". J. Biol. Chem. 280 (10): 9450–9. doi:. PMID 15623522.
- Jalota A, Singh K, Pavithra L, et al. (2005). "Tumor suppressor SMAR1 activates and stabilizes p53 through its arginine-serine-rich motif.". J. Biol. Chem. 280 (16): 16019–29. doi:. PMID 15701641.
- Rampalli S, Pavithra L, Bhatt A, et al. (2005). "Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex.". Mol. Cell. Biol. 25 (19): 8415–29. doi:. PMID 16166625.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:. PMID 16189514.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:. PMID 16344560.

