B-cell prolymphocytic leukemia
From Wikipedia, the free encyclopedia
| B-cell prolymphocytic leukemia Classification and external resources |
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| ICD-O: | 9833 |
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B-cell prolymphocytic leukemia is a more aggressive, but still treatable, form of chronic lymphocytic leukemia. The malignant B cells are larger than average. The name is commonly abbreviated B-PLL.
It can involve deletions from chromosome 11 and chromosome 13.[1]
It has a relatively poor prognosis.[2]
[edit] References
- ^ Lens D, Matutes E, Catovsky D, Coignet LJ (2000). "Frequent deletions at 11q23 and 13q14 in B cell prolymphocytic leukemia (B-PLL)". Leukemia 14 (3): 427–30. PMID 10720137.
- ^ Del Giudice I, Davis Z, Matutes E, et al (2006). "IgVH genes mutation and usage, ZAP-70 and CD38 expression provide new insights on B-cell prolymphocytic leukemia (B-PLL)". Leukemia 20 (7): 1231–7. doi:. PMID 16642047.
