AZI2

From Wikipedia, the free encyclopedia


5-azacytidine induced 2
Identifiers
Symbol(s) AZI2; NAP1; AZ2; TILP(S); tilp
External IDs OMIM: 609916 MGI: 1351332 HomoloGene: 8443
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 64343 27215
Ensembl ENSG00000163512 ENSMUSG00000039285
Refseq NM_022461 (mRNA)
NP_071906 (protein)		 NM_001048146 (mRNA)
NP_001041611 (protein)
Location Chr 3: 28.34 - 28.37 Mb Chr 9: 117.89 - 117.91 Mb
Pubmed search [1] [2]

5-azacytidine induced 2, also known as AZI2, is a human gene.[1]

AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: AZI2 5-azacytidine induced 2.

[edit] Further reading

  • Funami K, Sasai M, Ohba Y, et al. (2007). "Spatiotemporal mobilization of Toll/IL-1 receptor domain-containing adaptor molecule-1 in response to dsRNA.". J. Immunol. 179 (10): 6867-72. PMID 17982077. 
  • Sasai M, Shingai M, Funami K, et al. (2007). "NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction.". J. Immunol. 177 (12): 8676-83. PMID 17142768. 
  • Sasai M, Oshiumi H, Matsumoto M, et al. (2005). "Cutting Edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation.". J. Immunol. 174 (1): 27-30. PMID 15611223. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.". Nat. Cell Biol. 6 (2): 97-105. doi:10.1038/ncb1086. PMID 14743216. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Fujita F, Taniguchi Y, Kato T, et al. (2003). "Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling.". Mol. Cell. Biol. 23 (21): 7780-93. PMID 14560022. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Miyagawa J, Muguruma M, Aoto H, et al. (2000). "Isolation of the novel cDNA of a gene of which expression is induced by a demethylating stimulus.". Gene 240 (2): 289-95. PMID 10580148. 
 This article on a gene on chromosome 3 is a stub. You can help Wikipedia by expanding it.