Autoimmune lymphoproliferative syndrome
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| Autoimmune lymphoproliferative syndrome Classification and external resources |
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| OMIM | 601859 603909 |
|---|---|
| DiseasesDB | 33425 33424 |
Autoimmune lymphoproliferative syndrome is a form of lymphoproliferative disorder. It affects lymphocyte apoptosis.[1]
[edit] Presentation
Among the possible symptoms are splenomegaly and hepatomegaly.[2]
[edit] Classification
Types include:
- I - Canale-Smith syndrome[3][4]
- IA - Fas receptor (this form is the most common)[5]
- IB - Fas ligand
- II
- IIA - Caspase 10
- IIB - Caspase 8
- III - unknown
- IV - Neuroblastoma RAS viral oncogene homolog
[edit] References
- ^ Fleisher TA (2008). "The autoimmune lymphoproliferative syndrome: an experiment of nature involving lymphocyte apoptosis". Immunol. Res. 40 (1): 87–92. doi:. PMID 18193364.
- ^ Autoimmune Lymphoproliferative Syndrome (ALPS), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH). Retrieved on 2008-03-01.
- ^ synd/2128 at Who Named It
- ^ Canale VC, Smith CH (June 1967). "Chronic lymphadenopathy simulating malignant lymphoma". J. Pediatr. 70 (6): 891–9. PMID 4165068.
- ^ Autoimmune Lymphoproliferative Syndrome. Retrieved on 2008-03-01.
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